SCHEMBL7756747

SCHEMBL7756747

[O-][S+]1CNc2ccc(CCCCl)cc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9684064 0.95
SCHEMBL9685789 0.85 SKP2 (0.41)
SCHEMBL8114298 0.84 HRH1 (0.37)
SCHEMBL9684208 0.84 CA2 (0.36)
SCHEMBL7756732 0.79 DRD2 (0.45)
SCHEMBL7765516 0.78 RECQL (0.31)
SCHEMBL9204489 0.78 KDM4E (0.34)
SCHEMBL7759822 0.76 SIGMAR1 (0.48)
SCHEMBL7761424 0.76 SIGMAR1 (0.46)
SCHEMBL7761674 0.76 CYP1A2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673934-B1 Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2001-04-25 EP disclosed
CN-1050601-C Preparation and the pharmaceutical compositions which contain them ADIR (FR) 2000-03-22 CN disclosed
US-5512569-A SIGMA RECEPTOR DISORDERS; PSYCHOLOGICAL DISORDERS ADIR ET COMPAGNIE (FR) 1996-04-30 US disclosed
CN-1111626-A Preparation and the pharmaceutical compositions which contain them ADIR (FR) 1995-11-15 CN disclosed
EP-0673934-A1 Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1995-09-27 EP disclosed
US-5084469-A Analgesics ADIR ET COMPAGNIE (FR) 1992-01-28 US disclosed