Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9437760 | 0.90 | L3MBTL1 (0.41) | MAPTTP53CYP1A2ALOX15TSHR | |
| SCHEMBL9685789 | 0.81 | SKP2 (0.41) | TP53CYP1A2TSHRMAPK1HSD17B10 | |
| SCHEMBL9204489 | 0.80 | KDM4E (0.34) | CYP1A2KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL5494452 | 0.79 | SKP2 (0.37) | TP53HIF1AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL27321209 | 0.78 | SIGMAR1 (0.51) | ADRA2CADRA1AADRA2BSIGMAR1CHRM1 | |
| SCHEMBL7756747 | 0.78 | — | — | |
| SCHEMBL8114298 | 0.77 | HRH1 (0.37) | CYP1A2SIGMAR1HTR2A | |
| SCHEMBL7765516 | 0.76 | RECQL (0.31) | — | |
| SCHEMBL9208886 | 0.76 | IDH1 (0.39) | CYP1A2TSHRLMNATAAR1ADRA2A | |
| SCHEMBL7761674 | 0.72 | CYP1A2 (0.41) | CYP1A2ALOX15SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0478446-A1 | Heterocyclic alkylamines, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-04-01 | — | — | EP | disclosed |