Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194369 | 0.83 | TSHR (0.46) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL9162523 | 0.81 | L3MBTL1 (0.45) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL8159185 | 0.79 | L3MBTL1 (0.39) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL27547929 | 0.79 | KDM4E (0.41) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL14812491 | 0.79 | L3MBTL1 (0.39) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL2963308 | 0.79 | TSHR (0.46) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL4858555 | 0.79 | L3MBTL1 (0.44) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| Hydrochloric Acid SCHEMBL20599523 | 0.78 | TSHR (0.44) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL28864594 | 0.78 | L3MBTL1 (0.42) | L3MBTL1TSHRHSD17B10KDM4ELMNA | |
| SCHEMBL465226 | 0.76 | LMNA (0.45) | L3MBTL1TSHRLMNAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0489877-B1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | UPJOHN CO (US) | 1995-09-20 | — | — | EP | disclosed |
| US-5302613-A | Antiatheroscleroic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1994-04-12 | — | — | US | disclosed |
| US-5252735-A | Antiatherosclerotic and antithrombotic 2-amino-6-phenyl-4H-pyran-4-ones | THE UPJOHN COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0489877-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES. | UPJOHN CO (US) | 1992-06-17 | — | — | EP | disclosed |
| WO-1992000290-A1 | ANTIATHEROSCLEROTIC AND ANTITHROMBOTIC 2-AMINO-6-PHENYL-4H-PYRAN-4-ONES | THE UPJOHN COMPANY (US) | 1992-01-09 | — | — | WO | disclosed |