Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.46 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 8/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | PLOD2 | O00469 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27516724 | 0.83 | KMT2A (0.42) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| SCHEMBL5948412 | 0.83 | CES2 (0.44) | HPGDSMN1; SMN2MAPTCES1NPC1 | |
| SCHEMBL210845 | 0.83 | ALDH1A1 (0.38) | KMT2AMEN1HPGDMAPTKDM4E | |
| SCHEMBL7400361 | 0.80 | NPC1 (0.33) | SMN1; SMN2MAPTCES1NPC1RAB9A | |
| SCHEMBL28139107 | 0.75 | HPGD (0.40) | KMT2AHPGDSMN1; SMN2MAPTKDM4E | |
| SCHEMBL7094536 | 0.72 | KMT2A (0.34) | KMT2AMEN1HPGDSMN1; SMN2MAPT | |
| SCHEMBL10785589 | 0.71 | — | — | |
| SCHEMBL31219417 | 0.71 | L3MBTL1 (0.36) | KMT2AMEN1HPGDMAPTMAPK1 | |
| SCHEMBL3265216 | 0.71 | CES1 (0.33) | KMT2AMAPTCES1 | |
| Dibenzoylmethane SCHEMBL21597905 | 0.70 | MEN1 (0.94) | KMT2AMEN1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5433896-A | FLUORESCENT | MOLECULAR PROBES, INC. (US) | 1995-07-18 | — | — | US | disclosed |