Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | POLQ | O75417 | 12/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9198607 | 0.83 | MAPT (0.36) | — | |
| SCHEMBL7180799 | 0.76 | IDO1 (0.40) | AR | |
| SCHEMBL8201118 | 0.76 | CHRNB2 (0.39) | PDK2GPBAR1 | |
| SCHEMBL9204753 | 0.76 | CHRNB2 (0.44) | PGRPDK2GPBAR1 | |
| SCHEMBL3954105 | 0.68 | DHODH (0.37) | — | |
| SCHEMBL1224926 | 0.68 | AR (0.31) | AR | |
| SCHEMBL17100731 | 0.68 | DHODH (0.42) | ARS1PR1 | |
| SCHEMBL9638607 | 0.67 | ALDH1A1 (0.31) | — | |
| SCHEMBL8606823 | 0.65 | AR (0.37) | ARNOTUM | |
| SCHEMBL8607171 | 0.64 | CACNA1B (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0484223-B1 | 3-Cycloalkylpropanamides, their tautomers and salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL UCLAF (FR) | 1995-03-08 | — | — | EP | disclosed |
| US-5384423-A | Intermediates for antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1995-01-24 | — | — | US | disclosed |
| US-5240960-A | Antiinflammatory agents | ROUSSEL UCLAF (FR) | 1993-08-31 | — | — | US | disclosed |
| EP-0484223-A2 | 3-Cycloalkylpropanamides, their tautomers and salts, process for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1992-05-06 | — | — | EP | disclosed |