SCHEMBL920647

SCHEMBL920647

CC(C)Cc1cccc(CNC(=O)c2cccnc2N)c1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.48
KMT2A Q03164 2/20 0.48
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
HSD17B10 Q99714 1/20 0.48
NSD2 O96028 1/20 0.48
USP2 O75604 1/20 0.46
PIK3CD O00329 1/20 0.46
POLB P06746 2/20 0.44
ESR1 P03372 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTT P42858 1/20 0.44
PRKCI P41743 2/20 0.44
MAPK8 P45983 1/20 0.44
ATM Q13315 1/20 0.44
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43
LMNA P02545 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920245 0.86 HPGD (0.54) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL921620 0.86 MAPK8 (0.52) HPGDKMT2AALDH1A1KDM4EUSP2
SCHEMBL27803858 0.85 NSD2 (0.52) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL922756 0.84 HPGD (0.52) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL922567 0.84 HPGD (0.68) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL923436 0.83 NSD2 (0.56) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL922032 0.83 NSD2 (0.56) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL920053 0.83 MAPK8 (0.52) HPGDKMT2AALDH1A1POLBMAPK8
SCHEMBL921415 0.83 ROCK2 (0.53) HPGDKMT2AALDH1A1KDM4EHSD17B10
SCHEMBL922788 0.82 HPGD (0.50) HPGDKMT2AALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885KMT2A 2469/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.