Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.44 |
| ▸ | PHOSPHO1 | Q8TCT1 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | CCR6 | P51684 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | TLR2 | O60603 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9210053 | 0.83 | SLC6A9 (0.47) | GLSCYP11B1CYP11B2SLC6A9GAA | |
| SCHEMBL8433358 | 0.78 | GLS (0.46) | GLSCYP11B1CYP11B2GAAKDR | |
| SCHEMBL9206083 | 0.77 | MAPT (0.40) | GLSPHOSPHO1CYP11B2SLC6A9FGFR4 | |
| SCHEMBL10347988 | 0.76 | PHOSPHO1 (0.43) | PHOSPHO1SLC6A9GAAFGFR4KIF11 | |
| SCHEMBL6504211 | 0.75 | GAA (0.52) | GAAFGFR4PKMMAPT | |
| SCHEMBL8522013 | 0.74 | GLS (0.50) | GLSPKMKDRMAPT | |
| SCHEMBL9207012 | 0.74 | SLC6A9 (0.47) | SLC6A9GAAFGFR4MAPT | |
| SCHEMBL28134313 | 0.73 | ALDH1A1 (0.40) | GLSNR3C1SLC6A9PKMMAPT | |
| SCHEMBL10770318 | 0.73 | MEN1 (0.47) | GAAFGFR4PKMKDRMAPT | |
| SCHEMBL10769007 | 0.73 | PKM (0.46) | PHOSPHO1GAAFGFR4PKMKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0544218-B1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL CO (JP) | 1995-07-26 | — | — | EP | disclosed |
| US-5266556-A | Herbicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-30 | — | — | US | disclosed |
| EP-0544218-A1 | Arylindazole derivatives and their use | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-06-02 | — | — | EP | disclosed |