Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NPY1R | P25929 | 1/20 | 0.54 |
| ▸ | NPY2R | P49146 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CTSV | O60911 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422728 | 0.80 | ALDH1A1 (0.62) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL27543191 | 0.77 | DRD2 (0.52) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL30312308 | 0.75 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL4011471 | 0.75 | ALDH1A1 (0.68) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL8995335 | 0.74 | ALOX5 (0.56) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL10602238 | 0.74 | ALOX5 (0.59) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL8310270 | 0.73 | CYP19A1 (0.62) | MEN1KMT2AALDH1A1POLBMAPT | |
| SCHEMBL28196967 | 0.73 | MAPT (0.54) | MEN1KMT2AALDH1A1MAPTHTT | |
| SCHEMBL10600299 | 0.72 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1POLBPKM | |
| SCHEMBL27287105 | 0.72 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0650599-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | OXIS INTERNATIONAL S.A. (FR) | 1995-05-03 | — | — | EP | disclosed |
| WO-1994027155-A1 | METHOD OF COLORIMETRIC ANALYSIS OF MALONIC DIALDEHYDE AND 4-HYDROXY-2-ENALDEHYDES AS INDEXES OF LIPID PEROXIDATION, KITS FOR CARRYING OUT SAID METHOD, SUBSTITUTED INDOLES FOR USE IN SAID METHOD AND THEIR PREPARATION | BIOXYTECH (FR) | 1994-11-24 | — | — | WO | disclosed |