Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.48 |
| ▸ | TUBB | P07437 | 1/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27543191 | 0.80 | DRD2 (0.52) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8856056 | 0.78 | ALOX5 (0.68) | ALOX5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL13436536 | 0.77 | MTNR1A (0.71) | ALDH1A1KDM4EHPGDHSD17B10TSHR | |
| SCHEMBL2545860 | 0.77 | TUBB4A (0.80) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3356338 | 0.77 | ALOX5 (0.71) | ALOX5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL7035552 | 0.75 | PTGS2 (0.56) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL13399698 | 0.75 | ALOX5 (0.68) | ALOX5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9208428 | 0.74 | MEN1 (0.54) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7897979 | 0.74 | CYP11B2 (0.66) | ALOX5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL4374342 | 0.73 | ALDH1A1 (0.68) | ALOX5ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5496844-A | Indole derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0639567-A1 | INDOLE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 1995-02-22 | — | — | EP | disclosed |