Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | TTPA | P49638 | 2/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Raxofelast SCHEMBL633620 | 1.00 | THRA (0.40) | THRATHRBMEN1KMT2APDE4A | |
| SCHEMBL9786760 | 0.88 | MEN1 (0.36) | THRATHRBMEN1KMT2APDE4A | |
| SCHEMBL9201691 | 0.86 | MEN1 (0.37) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9201685 | 0.86 | MEN1 (0.37) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9208447 | 0.86 | THRA (0.41) | THRATHRBIMPDH2IMPDH1KDM4E | |
| SCHEMBL9786771 | 0.86 | MIF (0.36) | THRATHRBMEN1KMT2APDE4A | |
| SCHEMBL8599903 | 0.85 | MEN1 (0.38) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9851204 | 0.84 | MEN1 (0.37) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL10473653 | 0.83 | MEN1 (0.36) | MEN1KMT2APDE4APDE3ATTPA | |
| SCHEMBL9207314 | 0.82 | TTPA (0.39) | MEN1KMT2APDE4APDE3ATTPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 375 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328323-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | SATYAM APPARAO (IN) | 2015-11-19 | — | — | US | claimed |
| WO-2014111957-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | SATYAM APPARAO (IN) | 2014-07-24 | — | — | WO | claimed |
| US-8541607-B2 | Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses thereof | LACER, S.A. (ES) | 2013-09-24 | — | — | US | claimed |
| EP-2560634-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | Piramal Enterprises Limited (IN) | 2013-02-27 | — | — | EP | claimed |
| JP-4809769-B2 | — | — | 2011-11-09 | — | — | JP | claimed |
| WO-2011132171-A1 | NITRIC OXIDE RELEASING PRODRUGS OF THERAPEUTIC AGENTS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | WO | claimed |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2011-10-27 | — | — | US | claimed |
| US-20100196387-A1 | Disulfide, Sulfide, Sulfoxide, and Sulfone Derivatives of Cyclic Sugars and Uses Thereof | LACER, S.A. (ES) | 2010-08-05 | — | — | US | claimed |
| EP-1668017-B1 | DISULFIDE, SULFIDE, SULFOXIDE, AND SULFONE DERIVATIVES OF CYCLIC SUGARS AND USES THEREOF | LACER SA (ES) | 2009-02-25 | — | — | EP | claimed |
| CN-1863805-A | Disulfide, sulfide, sulfoxide and sulfone derivatives of cyclic sugars and uses thereof | LACER SA (ES) | 2006-11-15 | — | — | CN | claimed |
| US-20060235052-A1 | Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses | LACER S.A. (ES) | 2006-10-19 | — | — | US | claimed |
| EP-1668017-A1 | DISULFIDE, SULFIDE, SULFOXIDE, AND SULFONE DERIVATIVES OF CYCLIC SUGARS AND USES THEREOF | LACER, S.A. (ES) | 2006-06-14 | — | — | EP | claimed |
| WO-2005037842-A1 | DISULFIDE, SULFIDE, SULFOXIDE, AND SULFONE DERIVATIVES OF CYCLIC SUGARS AND USES THEREOF | LÁCER, S.A. (ES) | 2005-04-28 | — | — | WO | claimed |
| EP-1336602-A1 | Nitrate prodrugs able to release nitric oxide in a controlled and selective way and their use for prevention and treatment of inflammatory, ischemic and proliferative diseases | Scaramuzzino, Giovanni (IT) | 2003-08-20 | — | — | EP | claimed |
| US-20030134332-A1 | Diagnosis of endothelial dysfunction by nitric oxide bioactivity index | BOYKIN JOSEPH V (US) | 2003-07-17 | — | — | US | claimed |
| WO-2003045910-A2 | DIAGNOSIS OF ENDOTHELIAL DYSFUNCTION BY NITRIC OXIDE BIOACTIVITY INDEX | BOYKIN JOSEPH V JR (US) | 2003-06-05 | — | — | WO | claimed |
| JP-2078675-A | — | — | None | — | — | JP | disclosed |
| EP-4705765-A2 | BUCCAL CELL DIAGNOSIS OF RISK IN FAMILIAL ARRHYTHMIA SYNDROMES | Beth Israel Deaconess Medical Center, Inc. (US) | 2026-03-11 | — | — | EP | disclosed |
| US-4999350-A | PREVENTION OF TISSUE DAMAGE FROM FREE RADICALS AND OXIDIZING METABOLITES | BIOMEDICA FOSCAMA INDUSTRIA CHIMICO-FARMACEUTICA S.P.A. (IT) | 1991-03-12 | — | — | US | disclosed |
| JP-H0278675-A | BENZOFRANYL ACETATE DERIVATIVE, ITS PRODUCTION, MUCUS REGULATOR AND ANTIHISTAMIC AGENT | BIOMEDICA FOSCAMA IND CHIM FARMACEUT SPA | 1990-03-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060235052-A1 | Disulfide, sulfide, sulfoxide, and sulfone derivatives of cyclic sugars and uses | TST, STS, SORD | THRA 3116/4885THRB 1967/4885MEN1 2741/4885 |
| US-20100196387-A1 | Disulfide, Sulfide, Sulfoxide, and Sulfone Derivatives of Cyclic Sugars and Uses Thereof | TST, STS, SORD | THRA 2577/4885THRB 1552/4885MEN1 2695/4885 |
| US-20110263526-A1 | Nitric Oxide Releasing Prodrugs of Therapeutic Agents | NOS2, NOS1, NOS3 | THRA 1994/4885THRB 2021/4885MEN1 2829/4885 |
| US-20150328323-A1 | Nitric Oxide Releasing Produgs of Therapeutic Agents | NOS2, NOS1, PTGIS | THRA 1916/4885THRB 2436/4885MEN1 2312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.