Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 10/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9770869 | 0.70 | HDAC3 (0.38) | LMNASMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL7583374 | 0.60 | TP53 (0.41) | ALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL14119898 | 0.59 | LMNA (1.00) | LMNASMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL14119869 | 0.58 | LMNA (0.73) | LMNASMN1; SMN2ALDH1A1GAAMEN1 | |
| SCHEMBL28518947 | 0.58 | RORC (0.51) | SMN1; SMN2ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL1539261 | 0.58 | NPC1 (0.36) | LMNASMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL7921629 | 0.58 | CYP3A4 (0.45) | LMNASMN1; SMN2ALDH1A1GAAMEN1 | |
| SCHEMBL11288577 | 0.56 | L3MBTL1 (0.49) | LMNASMN1; SMN2ALDH1A1GAAMEN1 | |
| SCHEMBL25395345 | 0.55 | — | — | |
| SCHEMBL3202257 | 0.55 | KIF11 (0.38) | LMNASMN1; SMN2ALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0414112-B1 | Herbicides thiadiazabicyclononan derivatives | BASF AG (DE) | 1995-12-20 | — | — | EP | disclosed |
| US-5106408-A | Pre- and postemergence | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-21 | — | — | US | disclosed |
| EP-0414112-A2 | Herbicides thiadiazabicyclononan derivatives | BASF Aktiengesellschaft (DE) | 1991-02-27 | — | — | EP | disclosed |