Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGAV | P06756 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | ITGB5 | P18084 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832726 | 1.00 | LMNA (0.36) | LMNATDP1CYP19A1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9212026 | 0.85 | MMP2 (0.34) | LMNACYP19A1ALDH1A1MMP2ANPEP | |
| SCHEMBL8832958 | 0.85 | MMP2 (0.34) | LMNACYP19A1ALDH1A1MMP2ANPEP | |
| SCHEMBL9215805 | 0.83 | DRD2 (0.37) | CYP19A1MMP2FAAHMGLL | |
| SCHEMBL8834267 | 0.83 | DRD2 (0.37) | CYP19A1MMP2FAAHMGLL | |
| SCHEMBL8833376 | 0.82 | SIGMAR1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9220610 | 0.82 | SIGMAR1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9025956 | 0.80 | CYP19A1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9027934 | 0.80 | CYP19A1 (0.33) | CYP19A1MMP2ANPEP | |
| SCHEMBL9215991 | 0.80 | ECE1 (0.34) | CYP19A1ALDH1A1FAAHMAPK1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0636133-A1 | SUBSTITUTED 3-PYRROLIDINYLTHIO-CARBAPENEMS AS ANTIMICROBIAL AGENTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-02-01 | — | — | EP | disclosed |