SCHEMBL921797

SCHEMBL921797

COCc1ccc(C(=O)NCc2ccc(Oc3ccccc3CCC(C)C)cc2)c(N)n1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 2/20 0.42
PRMT6 Q96LA8 2/20 0.42
HPGD P15428 4/20 0.40
ALDH1A1 P00352 3/20 0.40
GAA P10253 2/20 0.40
HTT P42858 2/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
PKM P14618 1/20 0.38
MAPK14 Q16539 1/20 0.38
EGFR P00533 1/20 0.37
RORC P51449 1/20 0.37
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
PLA2G1B P04054 1/20 0.37
ATG4B Q9Y4P1 1/20 0.37
PTGER4 P35408 1/20 0.37
PTGER2 P43116 1/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919648 0.91 CARM1 (0.43) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL921327 0.90 HPGD (0.44) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL920235 0.90 EGLN1 (0.38) CARM1PRMT6HPGDALDH1A1HTT
SCHEMBL922047 0.89 HPGD (0.43) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL919238 0.89 ALDH1A1 (0.42) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL921334 0.88 ALDH1A1 (0.42) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL922806 0.88 CARM1 (0.43) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL921168 0.87 PPARA (0.42) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL921959 0.87 CARM1 (0.43) CARM1PRMT6HPGDALDH1A1GAA
SCHEMBL919543 0.86 KDM4E (0.41) HPGDALDH1A1MAPK14PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 CARM1 273/4885PRMT6 1994/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.