Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MMP12 | P39900 | 2/20 | 0.44 |
| ▸ | GABRP | O00591 | 1/20 | 0.44 |
| ▸ | GABRD | O14764 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212149 | 0.96 | SCN2A (0.50) | HPGDCYP1A2CYP3A4CYP2C19MMP3 | |
| SCHEMBL9218881 | 0.92 | SMN1; SMN2 (0.55) | HPGDMMP3SCN2ASCN10ATP53 | |
| SCHEMBL9219766 | 0.88 | ALDH1A1 (0.53) | HPGDMMP3SCN2ASCN10ATP53 | |
| SCHEMBL9216907 | 0.83 | ALDH1A1 (0.53) | HPGDMMP3SCN2ASCN10ATP53 | |
| SCHEMBL9217404 | 0.82 | SMN1; SMN2 (0.60) | CYP2C19MMP3TP53SMN1; SMN2LMNA | |
| SCHEMBL9216807 | 0.81 | ALDH1A1 (0.52) | HPGDCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL9218746 | 0.81 | NAAA (0.48) | ALDH1A1CNR1 | |
| SCHEMBL9211748 | 0.80 | ADORA3 (0.49) | HPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL9221111 | 0.80 | ALDH1A1 (0.51) | HPGDCYP1A2CYP3A4CYP2C19TP53 | |
| SCHEMBL9213606 | 0.80 | SMN1; SMN2 (0.56) | HPGDCYP1A2CYP3A4CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-B1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| CN-1067886-A | New urea derivatives, their preparation method and pharmaceutical composition thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1993-01-13 | — | — | CN | disclosed |
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |