Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | FDPS | P14324 | 1/20 | 0.45 |
| ▸ | ANPEP | P15144 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133806 | 0.85 | LMNA (0.57) | LMNAOPRM1OPRD1OPRK1MEN1 | |
| Hydrochloric Acid SCHEMBL4987504 | 0.83 | LMNA (0.56) | LMNAGAATAAR1SIGMAR1OPRM1 | |
| Phenylethyl Carbamate SCHEMBL111316 | 0.82 | LMNA (0.79) | LMNACA1CA2TDP1ALDH1A1 | |
| SCHEMBL28906679 | 0.81 | LMNA (0.54) | LMNAGAATDP1KDM4EALDH1A1 | |
| Phenylethyl Carbamate SCHEMBL29827053 | 0.81 | LMNA (0.61) | LMNATAAR1MEN1KMT2ACA12 | |
| SCHEMBL11307950 | 0.80 | THRB (0.56) | GAATAAR1SIGMAR1MEN1KMT2A | |
| SCHEMBL7273307 | 0.80 | GAA (0.55) | GAATAAR1SIGMAR1OPRM1MEN1 | |
| Phenprobamate SCHEMBL134496 | 0.79 | LMNA (1.00) | LMNAMEN1KMT2ATDP1MAPT | |
| SCHEMBL23045236 | 0.78 | LMNA (0.46) | LMNA | |
| SCHEMBL2432448 | 0.78 | KCNH2 (0.50) | LMNAOPRM1OPRD1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655055-A1 | TACHYKININ ANTAGONISTS | WARNER-LAMBERT COMPANY (US) | 1995-05-31 | — | — | EP | disclosed |