Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218339 | 0.92 | APP (0.34) | HRH3ACHEAPPSCN9A | |
| SCHEMBL9218033 | 0.83 | ACHE (0.47) | HRH3ACHE | |
| SCHEMBL9218017 | 0.83 | ACHE (0.47) | HRH3ACHE | |
| SCHEMBL9217125 | 0.82 | ACHE (0.46) | HRH3ACHESCN9A | |
| SCHEMBL9217113 | 0.79 | L3MBTL1 (0.35) | HRH3APP | |
| SCHEMBL9216482 | 0.79 | L3MBTL1 (0.33) | HRH3APP | |
| Fumaric Acid SCHEMBL29754133 | 0.77 | ACHE (0.44) | HRH3ACHE | |
| SCHEMBL9212403 | 0.77 | ALDH1A1 (0.32) | HRH3 | |
| SCHEMBL9216873 | 0.75 | CHRM2 (0.41) | SCN9A | |
| SCHEMBL9213773 | 0.74 | ACHE (0.38) | HRH3ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413343-B1 | Furan derivatives | KYOWA HAKKO KOGYO KK (JP) | 1995-08-02 | — | — | EP | disclosed |
| US-5075301-A | FURAN DERIVATIVES USEFUL FOR THE TREATMENT OF GASTRO-INTESTINAL DISORDERS | KYOWA HAKKO KOGYO, CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0413343-A2 | Furan derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-02-20 | — | — | EP | disclosed |