SCHEMBL921284

SCHEMBL921284

CCCCOc1ncc(CNC(=O)c2cccnc2N)s1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.43
HSD17B10 Q99714 1/20 0.43
PRKCI P41743 2/20 0.40
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
KDM4E B2RXH2 1/20 0.39
PIK3CD O00329 1/20 0.38
VCP P55072 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TSHR P16473 2/20 0.38
HDAC6 Q9UBN7 1/20 0.38
NAPRT Q6XQN6 1/20 0.37
SLC8A1 P32418 1/20 0.37
FAAH O00519 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13687722 0.87 PRKCI (0.43) HPGDPRKCILMNASMN1; SMN2KDM4E
SCHEMBL922870 0.83 SGMS2 (0.46) PRKCILMNAKDM4E
SCHEMBL1680941 0.82 MAPK8 (0.51) PRKCIKDM4EALDH1A1SLC8A1
SCHEMBL920943 0.79 ALDH1A1 (0.47) HPGDPRKCILMNASMN1; SMN2KDM4E
SCHEMBL920132 0.79 LMNA (0.58) HPGDHSD17B10LMNASMN1; SMN2TSHR
SCHEMBL13491553 0.78 PLK1 (0.49) HPGDHSD17B10LMNASMN1; SMN2ALDH1A1
SCHEMBL922835 0.77 LMNA (0.56) HPGDHSD17B10LMNASMN1; SMN2TSHR
SCHEMBL922146 0.76 LMNA (0.55) HPGDHSD17B10LMNASMN1; SMN2TSHR
SCHEMBL920970 0.76 LMNA (0.55) HPGDHSD17B10LMNASMN1; SMN2TSHR
SCHEMBL920791 0.75 HPGD (0.58) HPGDHSD17B10LMNASMN1; SMN2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101951771-A Composition for agricultural use for controlling or preventing plant diseases caused by plant pathogens SUMITOMO CHEMICAL CO 2011-01-19 CN disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885HSD17B10 1285/4885PRKCI 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.