SCHEMBL921286

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL920695	0.92	MAPK14 (0.55)	ADORA2AADORA1CHRM4FLT1LRRK2
	SCHEMBL920890	0.91	MMP13 (0.52)	ADORA2AADORA1CHRM4FLT1LRRK2
	SCHEMBL921155	0.91	ADORA2A (0.47)	ADORA2AADORA1CHRM4FLT1LRRK2
	SCHEMBL919964	0.91	MAPK14 (0.57)	ADORA2AADORA1HPGDALDH1A1CYP3A4
	SCHEMBL919972	0.89	ADORA2A (0.46)	ADORA2AADORA1CHRM4FLT1LRRK2
	SCHEMBL920459	0.89	LIPG (0.55)	ADORA2AADORA1CHRM4CYP3A4SMN1; SMN2
	SCHEMBL921033	0.89	ADORA2A (0.53)	ADORA2AADORA1CHRM4HPGDALDH1A1
	SCHEMBL922074	0.89	ADORA2A (0.46)	ADORA2AADORA1CHRM4FLT1LRRK2
	SCHEMBL920568	0.89	MMP13 (0.57)	CHRM4FLT1LRRK2HPGDALDH1A1
	SCHEMBL920312	0.88	HPGD (0.50)	ADORA2AADORA1CHRM4FLT1LRRK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.