Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214315 | 0.85 | ABCB1 (0.56) | ABCB1SLC6A4TMEM97SIGMAR1 | |
| SCHEMBL9205156 | 0.84 | CHRNB2 (0.54) | KMT2ALTA4HKDM4EALDH1A1 | |
| SCHEMBL9210505 | 0.83 | HRH3 (0.57) | MEN1KMT2AACHEKDM4EALDH1A1 | |
| SCHEMBL9212384 | 0.83 | ADRA1A (0.52) | MEN1KMT2ALTA4HADRA1AADRA1B | |
| SCHEMBL10648297 | 0.82 | ABCB1 (0.45) | ABCB1MEN1KMT2ASIGMAR1DRD2 | |
| SCHEMBL9208504 | 0.76 | HRH2 (0.49) | KMT2ALTA4HTMEM97SIGMAR1KDM4E | |
| SCHEMBL9739469 | 0.73 | ABCB1 (0.55) | ABCB1SLC6A4TMEM97SIGMAR1 | |
| SCHEMBL9739220 | 0.72 | HRH3 (0.52) | SLC6A2SLC6A4KMT2AKDM4EALDH1A1 | |
| SCHEMBL9278988 | 0.71 | HRH3 (0.48) | — | |
| SCHEMBL9739552 | 0.71 | CHRNB2 (0.57) | MEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0410953-B1 | Piperidine compounds with glycosidase inhibition activity | MONSANTO CO (US) | 1995-11-08 | — | — | EP | disclosed |
| US-5175168-A | Glycosidase inhibitors | MONSANTO COMPANY (US) | 1992-12-29 | — | — | US | disclosed |
| US-5175157-A | Cardiovascular disorders | BOEHRINGER INGELHEIM GMBH (DE) | 1992-12-29 | — | — | US | disclosed |
| US-5025021-A | 1,2-dideoxy-2-fluoronojirimycin as glycosidase inhibitors | MONSANTO COMPANY (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0410953-A2 | Piperidine compounds with glycosidase inhibition activity | MONSANTO COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |