SCHEMBL921320

SCHEMBL921320

Cc1cccc(COc2ccc(CNC(=O)c3cccnc3N)cc2)c1

nearest known ligand 0.54

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HPGD P15428 5/20 0.54
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 1/20 0.54
HSD17B10 Q99714 1/20 0.54
MAOB P27338 1/20 0.50
KLKB1 P03952 1/20 0.50
LMNA P02545 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
POLB P06746 3/20 0.47
NPC1 O15118 1/20 0.47
ALOX12 P18054 1/20 0.47
HTT P42858 1/20 0.47
RAB9A P51151 1/20 0.47
MAPK8 P45983 1/20 0.47
MMP13 P45452 1/20 0.46
KMT2A Q03164 3/20 0.46
MEN1 O00255 2/20 0.46
MAPT P10636 2/20 0.46
RECQL P46063 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922644 0.92 HPGD (0.57) HPGDALDH1A1KDM4EHSD17B10MAOB
SCHEMBL922511 0.89 HPGD (0.60) HPGDALDH1A1KDM4EHSD17B10KLKB1
SCHEMBL923305 0.89 HPGD (0.60) HPGDALDH1A1KDM4EMAOBLMNA
SCHEMBL922567 0.88 HPGD (0.68) HPGDALDH1A1KDM4EHSD17B10POLB
SCHEMBL1680671 0.88 MAOB (0.54) MAOB
SCHEMBL922746 0.88 GID4 (0.57) ALDH1A1KDM4EMAOBKLKB1LMNA
SCHEMBL922540 0.87 MAPK8 (0.58) HPGDKLKB1LMNASMN1; SMN2HTT
SCHEMBL920714 0.86 MAPK8 (0.53) HPGDALDH1A1KDM4EHSD17B10LMNA
SCHEMBL921980 0.85 HPGD (0.64) HPGDALDH1A1LMNASMN1; SMN2POLB
SCHEMBL922884 0.85 MAPK8 (0.56) HPGDALDH1A1KDM4ESMN1; SMN2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885ALDH1A1 2743/4885KDM4E 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.