Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574835 | 0.82 | MAPT (0.58) | ALDH1A1MAPTMEN1GAAHTT | |
| SCHEMBL574469 | 0.82 | LGMN (0.50) | ALDH1A1MAPTALOX15MEN1GAA | |
| SCHEMBL21596383 | 0.78 | GAA (0.62) | MAPTMEN1GAAKMT2AKDM4E | |
| SCHEMBL6366966 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPTALOX15L3MBTL1MEN1 | |
| SCHEMBL20836338 | 0.75 | ALDH1A1 (0.41) | ALDH1A1MAPTALOX15L3MBTL1MEN1 | |
| SCHEMBL6485292 | 0.73 | ALDH1A1 (0.44) | ALDH1A1MAPTALOX15L3MBTL1MEN1 | |
| SCHEMBL20767820 | 0.72 | ALDH1A1 (0.43) | ALDH1A1MAPTALOX15L3MBTL1MEN1 | |
| SCHEMBL6607436 | 0.72 | IP6K1 (0.41) | ALDH1A1MAPTALOX15L3MBTL1MEN1 | |
| SCHEMBL2174173 | 0.71 | ALDH1A1 (0.67) | ALDH1A1MAPTALOX15L3MBTL1MEN1 | |
| SCHEMBL3608882 | 0.71 | ALDH1A1 (0.41) | ALDH1A1MAPTALOX15L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536169-B1 | [3H,7H]THIAZOLO [3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA (IT) | 1995-04-05 | — | — | EP | disclosed |
| US-5336676-A | [3H,7H]thiazolo[3,4-a]pyridines with antiasthmatic and antiinflammatory actions on the respiratory tract | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1994-08-09 | — | — | US | disclosed |
| EP-0536169-A1 | 3H,7H]THIAZOLO 3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT. | BOEHRINGER MANNHEIM ITALIA (IT) | 1993-04-14 | — | — | EP | disclosed |
| CN-1057263-A | [3H, 7H] thiazole that respiratory tract is had anti-asthma and an anti-inflammatory effect is [3,4-α] pyridine also | BOEHRINGER MANNHEIM ITALIA (IT) | 1991-12-25 | — | — | CN | disclosed |
| WO-1991018906-A1 | [3H,7H]THIAZOLO[3,4-a]PYRIDINES WITH ANTIASTHMATIC AND ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1991-12-12 | — | — | WO | disclosed |