Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10516708 | 0.83 | KDM4E (0.46) | P2RX7ALDH1A1KDM4EKIF18ASMN1; SMN2 | |
| SCHEMBL9364168 | 0.81 | JAK2 (0.41) | P2RX7POLBKIF18AEGFRSMN1; SMN2 | |
| SCHEMBL9117916 | 0.81 | SLC40A1 (0.48) | POLBALDH1A1KDM4ECA9MEN1 | |
| SCHEMBL9118803 | 0.80 | KIF18A (0.38) | P2RX7POLBALDH1A1KDM4EHPGD | |
| SCHEMBL8114615 | 0.75 | ALDH1A1 (0.46) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL9258845 | 0.75 | USP30 (0.36) | POLBALDH1A1KDM4EHPGDKIF18A | |
| SCHEMBL9522703 | 0.73 | SLC40A1 (0.41) | ALDH1A1KDM4EHPGDSMN1; SMN2MEN1 | |
| SCHEMBL4970018 | 0.73 | P2RX7 (0.59) | P2RX7ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL9038749 | 0.73 | COMT (0.43) | POLBALDH1A1KDM4EHPGDSMN1; SMN2 | |
| SCHEMBL7458884 | 0.72 | ALDH1A1 (0.41) | P2RX7POLBALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5461026-A | Pyridine sulfonyl urea derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-10-24 | — | — | US | disclosed |
| EP-0639190-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1995-02-22 | — | — | EP | disclosed |
| WO-1992014728-A1 | PYRIDINE SULFONYL UREA DERIVATIVES | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1992-09-03 | — | — | WO | disclosed |