SCHEMBL921453

SCHEMBL921453

Fc1[c]cccc1OCc1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SYK P43405 14/20 0.49
ABCB1 P08183 2/20 0.49
HTR1A P08908 2/20 0.49
DRD2 P14416 2/20 0.49
AURKB Q96GD4 3/20 0.47
INCENP Q9NQS7 3/20 0.47
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
GABRA2 P47869 1/20 0.40
GCK P35557 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15475121 0.79 SYK (0.53) SYKABCB1HTR1ADRD2AURKB
SCHEMBL4569960 0.78 SYK (0.59) SYKABCB1HTR1ADRD2AURKB
SCHEMBL3211927 0.77 MAPT (0.50) HTR1ADRD2ALDH1A1
SCHEMBL921724 0.76 SMN1; SMN2 (0.50) ABCB1ALDH1A1SMN1; SMN2
SCHEMBL919555 0.75 IDO1 (0.51) ABCB1HTR1AALDH1A1
SCHEMBL920694 0.74 KDM4E (0.49) KDM4E
SCHEMBL920526 0.74 MCL1 (0.56) HTR1AKDM4EALDH1A1SMN1; SMN2
SCHEMBL1711774 0.74 SYK (0.46) SYKABCB1HTR1ADRD2AURKB
SCHEMBL920470 0.73 ALDH1A1 (0.50) HTR1AALDH1A1SMN1; SMN2
SCHEMBL3515049 0.73 SMN1; SMN2 (0.45) SYKABCB1HTR1ADRD2AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 SYK 1774/4885ABCB1 2966/4885HTR1A 4648/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 SYK 4330/4885ABCB1 4095/4885HTR1A 3327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.