SCHEMBL920694

SCHEMBL920694

Fc1[c]cccc1Oc1ccccn1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
KMT2A Q03164 2/20 0.37
MEN1 O00255 1/20 0.37
SCN9A Q15858 2/20 0.36
CD274 Q9NZQ7 1/20 0.36
SLC1A5 Q15758 1/20 0.34
PDE4A P27815 1/20 0.34
PDE4B Q07343 1/20 0.34
PDE4C Q08493 1/20 0.34
PDE4D Q08499 1/20 0.34
BLM P54132 2/20 0.33
LMNA P02545 1/20 0.33
CYP1A2 P05177 1/20 0.33
POLB P06746 1/20 0.33
CCR1 P32246 1/20 0.33
CCR5 P51681 1/20 0.33
CCR8 P51685 1/20 0.33
METAP1 P53582 1/20 0.33
HIF1A Q16665 1/20 0.33
DOHH Q9BU89 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29106580 0.82 KDM4E (0.44) KDM4EKMT2AMEN1SCN9ACD274
SCHEMBL919451 0.81 KMT2A (0.49) KDM4EKMT2AMEN1LTA4HPTGS2
SCHEMBL10507368 0.80 KDM4E (0.49) KDM4EKMT2AMEN1SCN9ACD274
SCHEMBL11138427 0.78 KDM4E (0.66) KDM4EKMT2AMEN1SLC1A5PDE4A
SCHEMBL18984674 0.77 MEN1 (0.59) KDM4EKMT2AMEN1SCN9ACD274
SCHEMBL9359315 0.76 KDM4E (0.63) KDM4EKMT2AMEN1SLC1A5PDE4A
SCHEMBL921453 0.74 SYK (0.49) KDM4E
SCHEMBL921640 0.74 KMT2A (0.59) KMT2AMEN1LMNAPOLB
Hydrochloric Acid SCHEMBL28670387 0.73 KDM4E (0.53) KDM4EKMT2AMEN1BLMLMNA
SCHEMBL920698 0.73 HTR1A (0.44) KDM4EKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 KDM4E 3657/4885KMT2A 2469/4885MEN1 4723/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 KDM4E 3733/4885KMT2A 1924/4885MEN1 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.