Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | PRKDC | P78527 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | ERN1 | O75460 | 7/20 | 0.50 |
| ▸ | KDM4A | O75164 | 1/20 | 0.46 |
| ▸ | KDM4B | O94953 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.44 |
| ▸ | ABAT | P80404 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2721914 | 0.85 | ALDH1A1 (0.53) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL9910897 | 0.85 | CYP3A4 (0.58) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL16838214 | 0.85 | ALDH5A1 (0.55) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL16838200 | 0.85 | ERN1 (0.55) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL5583374 | 0.85 | VCAM1 (0.55) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL4941249 | 0.85 | KDM4E (0.53) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL1094404 | 0.84 | ALDH1A1 (0.56) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL30412897 | 0.82 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL5610655 | 0.82 | ALOX15 (0.55) | ALDH1A1CYP3A4MAPTALOX15KDM4E | |
| SCHEMBL4988910 | 0.82 | HSD17B10 (0.55) | ALDH1A1CYP3A4MAPTALOX15KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0394846-B1 | Organic photochromic compound | SEIKISUI CHEMICAL CO LTD (JP) | 1995-06-14 | — | — | EP | disclosed |
| US-5091535-A | ORGANIC PHOTOCHROMIC COMPOUND, A DIMER OF PYRIDO QUINOLINE | SEIKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-02-25 | — | — | US | disclosed |
| EP-0394846-A2 | Organic photochromic compound | SEKISUI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-10-31 | — | — | EP | disclosed |