Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 9/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | KDM4B | O94953 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215364 | 0.85 | ALDH1A1 (0.62) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL13268302 | 0.79 | ALDH1A1 (0.41) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL2721914 | 0.76 | ALDH1A1 (0.53) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL16838214 | 0.76 | ALDH5A1 (0.55) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL5583374 | 0.76 | VCAM1 (0.55) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL9910897 | 0.76 | CYP3A4 (0.58) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL1094404 | 0.75 | ALDH1A1 (0.56) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL4941247 | 0.74 | CYP3A4 (0.47) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL14429392 | 0.74 | ALDH1A1 (0.47) | KDM4EALDH1A1CYP3A4MAPTALOX15 | |
| SCHEMBL5610655 | 0.73 | ALOX15 (0.55) | KDM4EALDH1A1CYP3A4MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012051659-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2012-04-26 | — | — | WO | disclosed |