Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 7/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.33 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.31 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9218481 | 0.91 | PTK2 (0.38) | PTK2TBXAS1MTNR1AKLKB1NFATC1 | |
| SCHEMBL9312295 | 0.90 | TBXAS1 (0.34) | TBXAS1MTNR1AKLKB1NFATC1KDM4E | |
| SCHEMBL9209687 | 0.84 | TBXAS1 (0.36) | TBXAS1MTNR1AKLKB1NFATC1KDM4E | |
| SCHEMBL9314703 | 0.81 | TBXAS1 (0.35) | TBXAS1MTNR1AKLKB1NFATC1KDM4E | |
| SCHEMBL9220655 | 0.79 | MAPT (0.41) | MEN1MAPTKMT2A | |
| SCHEMBL9215653 | 0.79 | FFAR1 (0.47) | MEN1KMT2A | |
| SCHEMBL9220714 | 0.78 | MTNR1A (0.47) | MTNR1AKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL9211264 | 0.77 | ALDH1A1 (0.34) | MTNR1AKDM4EMEN1CYP1A2CYP2D6 | |
| SCHEMBL9219061 | 0.76 | MAPT (0.43) | MTNR1AKDM4ECYP1A2MAPTHPGD | |
| SCHEMBL23987343 | 0.75 | NR4A2 (0.40) | KDM4EMEN1CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0433233-B1 | Heterocyclic compounds | CIBA GEIGY AG (CH) | 1995-01-25 | — | — | EP | disclosed |
| EP-0433233-A1 | Heterocyclic compounds | CIBA-GEIGY AG (CH) | 1991-06-19 | — | — | EP | disclosed |