Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | CHRNB3 | Q05901 | 2/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215626 | 0.78 | CHRNB4 (0.42) | ADRA2ACHRNB4CHRNA3CHRNB1CHRNB2 | |
| SCHEMBL9217936 | 0.78 | CHRNB2 (0.41) | CHRNB4CHRNA3CHRNB1CHRNB2CHRNA4 | |
| SCHEMBL9212260 | 0.76 | PDK1 (0.47) | PDK1ADRA2A | |
| SCHEMBL9218193 | 0.76 | CHRNB4 (0.43) | ADRA2ACHRNB4CHRNA3CHRNB1CHRNB2 | |
| SCHEMBL9744781 | 0.75 | TMEM97 (0.60) | — | |
| SCHEMBL9217289 | 0.74 | PDK1 (0.50) | PDK1 | |
| SCHEMBL7160856 | 0.73 | ADRA2A (0.47) | ADRA2ACHRNB4CHRNA3CHRNB1CHRNB2 | |
| SCHEMBL9206848 | 0.72 | PDK1 (0.50) | PDK1 | |
| SCHEMBL9208015 | 0.71 | PDK1 (0.63) | PDK1 | |
| SCHEMBL9275611 | 0.71 | PDK1 (0.58) | PDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405976-B1 | Azole derivatives and antiulcerative composition containing same | MEIJI SEIKA CO (JP) | 1995-04-05 | — | — | EP | disclosed |
| US-5200407-A | Antisecretory agents | MEIJI SEIKA KABURHIKI KAISHA (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5141946-A | Antisecretory agents; acid resistance | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5079255-A | Nontoxic, acid stability | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-01-07 | — | — | US | disclosed |