Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217936 | 0.81 | CHRNB2 (0.41) | TMEM97 | |
| SCHEMBL9743903 | 0.77 | TMEM97 (0.86) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9743348 | 0.77 | KCNH2 (0.43) | TMEM97ACP1 | |
| SCHEMBL9215426 | 0.75 | PDK1 (0.46) | — | |
| SCHEMBL8133052 | 0.73 | CYP1A2 (0.65) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9743754 | 0.73 | TMEM97 (0.68) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9622398 | 0.73 | SMN1; SMN2 (0.71) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL30423143 | 0.73 | SMN1; SMN2 (0.71) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9439564 | 0.72 | ALOX5 (0.64) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL9388713 | 0.72 | ALOX5 (0.61) | TMEM97ALOX5SMN1; SMN2NPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171746-A | THIAZOLE AND IMIDAZOLE DERIVATIVES AND ANTIULCER COMPOSITION CONTAINING SAME | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0452076-A1 | Thiazole and imidazole derivatives and antiulcer composition containing same | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1991-10-16 | — | — | EP | disclosed |