Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.55 |
| ▸ | BACE1 | P56817 | 1/20 | 0.55 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.47 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9025473 | 0.95 | CTSD (0.52) | CTSDBACE1BACE2CYP11B2CYP11B1 | |
| SCHEMBL10027761 | 0.82 | STK10 (0.48) | CTSDBACE1BACE2CYP11B2CYP11B1 | |
| SCHEMBL9218755 | 0.81 | ALDH1A1 (0.53) | CYP11B2CYP11B1KDM4ECYP17A1ALDH1A1 | |
| SCHEMBL29123961 | 0.81 | MAOB (0.57) | KDM4EALDH1A1USP2 | |
| SCHEMBL30196133 | 0.81 | KDM4E (0.70) | CYP11B2CYP11B1CYP19A1KDM4EMAPK1 | |
| SCHEMBL11342031 | 0.81 | KDM4E (0.70) | CYP11B2CYP11B1CYP19A1KDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL11336399 | 0.80 | KDM4E (0.68) | CYP11B2CYP11B1CYP19A1KDM4EMAPK1 | |
| SCHEMBL7279694 | 0.79 | PDGFRB (0.51) | CYP11B2CYP11B1CYP19A1KDM4ECYP17A1 | |
| SCHEMBL1911847 | 0.78 | NPC1 (0.65) | CTSDBACE1BACE2CYP11B2CYP11B1 | |
| SCHEMBL6439562 | 0.77 | CYP11B2 (0.56) | CYP11B2CYP11B1CYP19A1KDM4ECYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004052-A1 | METHYLGUANIDINE DERIVATIVES, METHODS FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAID DERIVATIVES | SANOFI (FR) | 1995-02-09 | — | — | WO | disclosed |