Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12436884 | 0.75 | HSD17B10 (0.47) | ALDH1A1KDM4EMAPTCA12CA1 | |
| SCHEMBL9208754 | 0.75 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL2817503 | 0.74 | MAOA (0.52) | LOXL2ALDH1A1IDO1CA12CA1 | |
| SCHEMBL9204195 | 0.70 | SMN1; SMN2 (0.47) | ALDH1A1MAPTNPC1RAB9AMEN1 | |
| SCHEMBL3913610 | 0.68 | L3MBTL1 (0.44) | LOXL2ALDH1A1MAPTKCNJ1 | |
| SCHEMBL19410323 | 0.67 | ALDH1A1 (0.50) | LOXL2ALDH1A1MAPTIDO1CA12 | |
| SCHEMBL9220984 | 0.67 | LOXL2 (0.42) | LOXL2ALDH1A1KDM4EMAPTIDO1 | |
| SCHEMBL9418914 | 0.66 | NPC1 (0.56) | LOXL2ALDH1A1MAPTCA12CA1 | |
| Hydrazine SCHEMBL27401571 | 0.66 | ALDH1A1 (0.74) | LOXL2ALDH1A1MAPTIDO1CA12 | |
| SCHEMBL22567 | 0.66 | ALDH1A1 (0.72) | LOXL2ALDH1A1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1995004053-A1 | UREA AND THIOUREA DERIVATIVES AND PROCESS FOR THEIR PREPARATION | PHARMACIA S.P.A. (IT) | 1995-02-09 | — | — | WO | disclosed |