Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9215528 | 0.90 | HTR7 (0.59) | HTR1AHTR7 | |
| SCHEMBL9221444 | 0.83 | SIGMAR1 (0.49) | — | |
| SCHEMBL9219564 | 0.83 | HTR1A (0.69) | HTR1AHTR7 | |
| SCHEMBL9219074 | 0.83 | HTR1A (0.66) | HTR1AHTR7 | |
| SCHEMBL9647583 | 0.82 | KDM4E (0.58) | MEN1KMT2ATSHRSMN1; SMN2SLC6A2 | |
| SCHEMBL9219866 | 0.82 | TMEM97 (0.49) | — | |
| SCHEMBL9210834 | 0.81 | DRD3 (0.58) | HTR2ASLC6A4MAPTHTR1AHTR7 | |
| SCHEMBL9597086 | 0.81 | TMEM97 (0.51) | — | |
| SCHEMBL9597365 | 0.79 | HTR7 (0.65) | SMN1; SMN2MAPTHTR1AHTR7 | |
| SCHEMBL9213014 | 0.78 | HTR1A (0.49) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487408-B1 | Oxazolopyridine derivatives, process for their preparation and pharmaceutical compositions comprising the same | ADIR (FR) | 1995-06-21 | — | — | EP | claimed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | claimed |
| US-5242923-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-09-07 | — | — | US | disclosed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | disclosed |