Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | GABRP | O00591 | 3/20 | 0.46 |
| ▸ | GABRD | O14764 | 3/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.46 |
| ▸ | GABRE | P78334 | 3/20 | 0.46 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.46 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.46 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.46 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.46 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6837648 | 0.83 | IKBKB (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31253326 | 0.80 | CYP1A2 (0.46) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL7537222 | 0.80 | CYP1A2 (0.46) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL445478 | 0.78 | NAPRT (0.50) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL29551348 | 0.78 | NAPRT (0.50) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL920297 | 0.78 | GABRP (0.64) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL11179056 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL4635194 | 0.77 | NAPRT (0.48) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| Hydrochloric Acid SCHEMBL2211447 | 0.77 | NAPRT (0.48) | NAPRTGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL8666506 | 0.77 | KDM4E (0.47) | NAPRTGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4383851-A | CONTROLLING WILD OATS IN WHEAT | THE DOW CHEMICAL COMPANY (US) | 1983-05-17 | — | — | US | claimed |
| US-20250019383-A1 | PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2025-01-16 | — | — | US | disclosed |
| CN-119039288-A | Pyrido [2,3-d ] pyrimidine derivatives as inhibitors of HIV replication | VIIV保健英国第五有限公司 | 2024-11-29 | — | — | CN | disclosed |
| US-12129255-B2 | Pyrido [2,3-d]pyrimidine derivatives as inhibitors of human immunodeficiency virus replication | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2024-10-29 | — | — | US | disclosed |
| CN-114245795-B | Pyrido [2,3-d ] pyrimidine derivatives as inhibitors of HIV replication | VIIV保健英国第五有限公司 | 2024-08-06 | — | — | CN | disclosed |
| EP-3986561-B1 | PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK NO 5 LTD (GB) | 2024-02-14 | — | — | EP | disclosed |
| US-20230355626-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV HEALTHCARE UK (NO. 5) LIMITED (GB) | 2023-11-09 | — | — | US | disclosed |
| US-20230212129-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2023-07-06 | — | — | US | disclosed |
| US-20230212129-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | Annji Pharmaceutical Co., Ltd. (TW) | 2023-07-06 | — | — | US | disclosed |
| EP-4114834-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2023-01-11 | — | — | EP | disclosed |
| WO-2021176366-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2021-09-10 | — | — | WO | disclosed |
| WO-2020254985-A1 | PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2020-12-24 | — | — | WO | disclosed |
| WO-2020254985-A1 | PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | VIIV Healthcare UK (No.5) Limited (GB) | 2020-12-24 | — | — | WO | disclosed |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| EP-2248423-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | Sumitomo Chemical Company, Limited (JP) | 2010-11-10 | — | — | EP | disclosed |
| US-5441955-A | Tuberculosis | PATHOGENESIS CORPORATION (US) | 1995-08-15 | — | — | US | disclosed |
| WO-1995013807-A1 | INDOLO[2,1-b]QUINAZOLINE-6,12-DIONE ANTIBACTERIAL COMPOUNDS AND METHODS OF USE THEREOF | PATHOGENESIS CORPORATION (US) | 1995-05-26 | — | — | WO | disclosed |
| US-4383851-A | CONTROLLING WILD OATS IN WHEAT | THE DOW CHEMICAL COMPANY (US) | 1983-05-17 | — | — | US | disclosed |
| US-4383851-A | CONTROLLING WILD OATS IN WHEAT | THE DOW CHEMICAL COMPANY (US) | 1983-05-17 | — | — | US | disclosed |
| US-4383851-A | CONTROLLING WILD OATS IN WHEAT | THE DOW CHEMICAL COMPANY (US) | 1983-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212129-A1 | QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS | HDAC6, HDAC1, HDAC5 | NAPRT 1605/4885GABRP 3777/4885GABRD 3702/4885 |
| US-20110009454-A1 | COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS | WIZ, TST, NAT1 | NAPRT 527/4885GABRP 3713/4885GABRD 3683/4885 |
| US-20250019383-A1 | PYRIDO[2,3-D]PYRIMIDINE DERIVATIVES AS INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | TYMP, TYMS, DPYD | NAPRT 105/4885GABRP 2395/4885GABRD 3558/4885 |
| US-12129255-B2 | Pyrido [2,3-d]pyrimidine derivatives as inhibitors of human immunodeficiency virus replication | TYMP, TYMS, DPYD | NAPRT 105/4885GABRP 2395/4885GABRD 3558/4885 |
| US-20230355626-A1 | INHIBITORS OF HUMAN IMMUNODEFICIENCY VIRUS REPLICATION | EIF2AK2, POLR2E, POLR2H | NAPRT 1288/4885GABRP 3435/4885GABRD 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.