SCHEMBL921706

SCHEMBL921706

Nc1ncccc1C(=O)NCc1cccc(Oc2ccc(C(F)(F)F)cc2F)c1

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.54
PPARD Q03181 11/20 0.54
PPARA Q07869 11/20 0.54
KCNQ3 O43525 1/20 0.53
KCNQ2 O43526 1/20 0.53
MAPK14 Q16539 1/20 0.48
HPGD P15428 1/20 0.46
KMT2A Q03164 1/20 0.46
SORT1 Q99523 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920754 0.93 KCNQ3 (0.51) PPARGPPARDPPARAKCNQ3KCNQ2
SCHEMBL921058 0.91 KCNQ3 (0.48) PPARGPPARDPPARAKCNQ3KCNQ2
SCHEMBL920195 0.89 MAPK14 (0.55) PPARGPPARDPPARAKCNQ3KCNQ2
SCHEMBL922154 0.88 PPARG (0.52) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL921323 0.88 MAPK14 (0.57) PPARGPPARDPPARAKCNQ3KCNQ2
SCHEMBL919713 0.87 MAPK8 (0.51) HPGDKMT2A
SCHEMBL920185 0.85 PPARG (0.51) PPARGPPARDPPARAMAPK14HPGD
SCHEMBL923196 0.84 GPR52 (0.49) PPARGPPARDPPARAKCNQ3KCNQ2
SCHEMBL922231 0.84 KMT2A (0.46) PPARGPPARDPPARAKCNQ3KCNQ2
SCHEMBL920054 0.84 MAPK8 (0.48) PPARGPPARDPPARAKCNQ3KCNQ2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARG 391/4885PPARD 360/4885PPARA 494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.