SCHEMBL923196

SCHEMBL923196

Nc1ncccc1C(=O)NCc1cccc(Oc2cc(F)cc(C(F)(F)F)c2)c1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GPR52 Q9Y2T5 2/20 0.49
KMT2A Q03164 3/20 0.46
HPGD P15428 2/20 0.46
MAPK14 Q16539 1/20 0.46
PPARG P37231 3/20 0.45
PPARD Q03181 3/20 0.45
PPARA Q07869 3/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
MAPK8 P45983 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
USP2 O75604 1/20 0.44
ALDH1A1 P00352 1/20 0.44
PIN1 Q13526 1/20 0.44
KCNQ3 O43525 1/20 0.43
KCNQ2 O43526 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920195 0.91 MAPK14 (0.55) KMT2AHPGDMAPK14PPARGPPARD
SCHEMBL920489 0.91 MAPK14 (0.48) GPR52KMT2AHPGDMAPK14MAPK8
SCHEMBL920802 0.89 MAPK14 (0.51) KMT2AHPGDMAPK14PPARGPPARD
SCHEMBL921323 0.89 MAPK14 (0.57) KMT2AHPGDMAPK14PPARGPPARD
SCHEMBL921259 0.88 KMT2A (0.53) KMT2AHPGDKDM4EMEN1MAPK8
SCHEMBL920670 0.85 MAPK8 (0.53) KMT2AHPGDMAPK14KDM4EMEN1
SCHEMBL919622 0.85 MAPK14 (0.54) KMT2AMAPK14KDM4EMEN1MAPK8
SCHEMBL920754 0.84 KCNQ3 (0.51) KMT2AHPGDMAPK14PPARGPPARD
SCHEMBL921706 0.84 PPARG (0.54) KMT2AHPGDMAPK14PPARGPPARD
SCHEMBL921954 0.84 HPGD (0.47) KMT2AHPGDMAPK14PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 GPR52 4701/4885KMT2A 2469/4885HPGD 1273/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.