Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361714 | 0.90 | ESR1 (0.46) | MAOATAAR1L3MBTL1TDP1 | |
| SCHEMBL7358383 | 0.90 | DPP4 (0.46) | MAOAMMP2TAAR1L3MBTL1LMNA | |
| SCHEMBL8475501 | 0.80 | MEN1 (0.55) | MMP2SMN1; SMN2CES2CES1 | |
| SCHEMBL8672567 | 0.77 | CES1 (0.52) | L3MBTL1TDP1MAPTCES2CES1 | |
| SCHEMBL9130252 | 0.75 | MEN1 (0.36) | TDP1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL9234138 | 0.75 | MAOA (0.37) | MAOAMMP2HTR2ASMN1; SMN2TAAR1 | |
| SCHEMBL8994830 | 0.75 | CES2 (0.47) | SMN1; SMN2L3MBTL1CES2CES1AKR1B1 | |
| SCHEMBL7373078 | 0.74 | MAOA (0.46) | MAOAMMP2HTR2AL3MBTL1TDP1 | |
| SCHEMBL9191695 | 0.71 | LTA4H (0.46) | HTR2ASMN1; SMN2L3MBTL1TDP1MAPT | |
| SCHEMBL7361543 | 0.71 | MAOA (0.46) | MAOAMMP2HTR2ALOXL2CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470834-A | Metalloproteinase enzyme inhibitors for arthritis, rheumatism and cancers | FLORIDA STATE UNIVERSITY (US) | 1995-11-28 | — | — | US | disclosed |