Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESRRG | P62508 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 3/20 | 0.35 |
| ▸ | CTSS | P25774 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | GUSB | P08236 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9217248 | 0.75 | MAOA (0.48) | NPC1CASP3RAB9ASENP8SENP7 | |
| SCHEMBL9534989 | 0.75 | MAOB (0.38) | MEN1KMT2AESR1ESRRGCTSL | |
| SCHEMBL8672567 | 0.74 | CES1 (0.52) | MEN1KMT2AALDH1A1TDP1CTSL | |
| SCHEMBL8475501 | 0.74 | MEN1 (0.55) | MEN1KMT2ACES2CES1 | |
| SCHEMBL2161768 | 0.73 | ESR1 (0.40) | KMT2AALDH1A1TDP1ESR1ESRRG | |
| SCHEMBL9185068 | 0.73 | TDP1 (0.64) | MEN1KMT2AALDH1A1NPC1CASP3 | |
| SCHEMBL8994830 | 0.72 | CES2 (0.47) | MEN1KMT2AESR1CES2CES1 | |
| SCHEMBL23981726 | 0.69 | MEN1 (0.39) | MEN1KMT2AALDH1A1CTSLCTSS | |
| SCHEMBL9191695 | 0.69 | LTA4H (0.46) | ALDH1A1NPC1CASP3RAB9ASENP8 | |
| SCHEMBL181369 | 0.69 | MEN1 (0.52) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430155-A | Viricides, treatment of AIDS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-04 | — | — | US | disclosed |