SCHEMBL921959

SCHEMBL921959

CC(C)CCc1ccccc1Oc1ccc(CNC(=O)c2ccc(F)nc2N)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.43
PRMT6 Q96LA8 3/20 0.43
PTGER4 P35408 3/20 0.43
PTGER2 P43116 1/20 0.43
HTT P42858 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
ALDH1A1 P00352 1/20 0.41
GAA P10253 1/20 0.41
HPGD P15428 1/20 0.41
ATM Q13315 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.40
MAOA P21397 1/20 0.40
PPARG P37231 1/20 0.40
PPARD Q03181 1/20 0.40
PPARA Q07869 1/20 0.40
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MAPK14 Q16539 1/20 0.39
CYP1A2 P05177 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921119 0.91 CARM1 (0.44) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL922806 0.90 CARM1 (0.43) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL920291 0.90 ALDH1A1 (0.46) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL919835 0.90 LIPG (0.43) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL921932 0.89 HTT (0.46) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL920777 0.88 ALDH1A1 (0.44) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL921292 0.87 ALDH1A1 (0.44) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL921797 0.87 CARM1 (0.42) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL920616 0.86 PPARA (0.43) CARM1PRMT6PTGER4PTGER2HTT
SCHEMBL920096 0.85 PPARG (0.41) ALDH1A1HPGDPPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 CARM1 273/4885PRMT6 1994/4885PTGER4 3181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.