Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9219866 | 0.84 | TMEM97 (0.49) | DRD2SIGMAR1 | |
| SCHEMBL9221444 | 0.83 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL9597086 | 0.83 | TMEM97 (0.51) | SIGMAR1 | |
| SCHEMBL9215528 | 0.82 | HTR7 (0.59) | HTR1AHTR7 | |
| SCHEMBL8871690 | 0.82 | DRD2 (0.59) | DRD2 | |
| SCHEMBL9591426 | 0.81 | KDM4E (0.49) | SLC18A3DRD2HTR1AADRA1BSIGMAR1 | |
| SCHEMBL9215613 | 0.77 | EGFR (0.48) | HTR1AHTR7 | |
| SCHEMBL9213014 | 0.77 | HTR1A (0.49) | HTR1AHTR7 | |
| SCHEMBL9219564 | 0.76 | HTR1A (0.69) | HTR1AHTR7 | |
| SCHEMBL9219074 | 0.76 | HTR1A (0.66) | HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487408-B1 | Oxazolopyridine derivatives, process for their preparation and pharmaceutical compositions comprising the same | ADIR (FR) | 1995-06-21 | — | — | EP | claimed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | claimed |
| US-5242923-A | Analgesics | ADIR ET COMPAGNIE (FR) | 1993-09-07 | — | — | US | disclosed |
| US-5130311-A | Analgesics or antiinflammatory agents | ADIR ET COMPAGNIE (FR) | 1992-07-14 | — | — | US | disclosed |