SCHEMBL9218591

SCHEMBL9218591

O=Nc1ccc(Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
HSD17B10 Q99714 2/20 0.53
CYP3A4 P08684 1/20 0.53
TSHR P16473 1/20 0.53
HTT P42858 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
AKR1C3 P42330 3/20 0.46
AKR1C2 P52895 2/20 0.46
RAPGEF4 Q8WZA2 1/20 0.42
KIF11 P52732 3/20 0.42
P2RX1 P51575 5/20 0.39
MAPT P10636 1/20 0.39
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
HDAC3 O15379 1/20 0.38
HDAC1 Q13547 1/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9220433 0.87 ALDH1A1 (0.59) ALDH1A1HSD17B10CYP3A4TSHRHTT
SCHEMBL9224466 0.85 KIF11 (0.60) ALDH1A1HSD17B10CYP3A4TSHRHTT
SCHEMBL23059923 0.81 AKR1C3 (0.50) AKR1C3AKR1C2RAPGEF4KIF11P2RX1
SCHEMBL394467 0.78 RAPGEF4 (0.59) AKR1C3AKR1C2RAPGEF4KIF11P2RX1
SCHEMBL16481311 0.77 APP (0.49) AKR1C3AKR1C2RAPGEF4KIF11P2RX1
SCHEMBL16481381 0.75 AKR1C3 (0.62) ALDH1A1HSD17B10TSHRHTTTDP1
SCHEMBL8231975 0.74 CES2 (0.46) ALDH1A1CYP3A4TSHRTDP1MAPT
SCHEMBL14256837 0.74 HTR3E (0.52) ALDH1A1HSD17B10CYP3A4TSHRKIF11
SCHEMBL29116639 0.74 AKR1C3 (0.69) HTTAKR1C3AKR1C2KIF11P2RX1
SCHEMBL9222756 0.72 ALDH1A1 (0.65) ALDH1A1HSD17B10CYP3A4TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0403797-B1 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN KK (JP) 1995-11-22 EP claimed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP claimed
EP-0403797-B1 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN KK (JP) 1995-11-22 EP disclosed
US-5318882-A Nitrosodiphenylamine compounds render dyes lightfast TAIYO YUDEN CO., LTD. (JP) 1994-06-07 US disclosed
EP-0403797-A2 The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye TAIYO YUDEN CO., LTD. (JP) 1990-12-27 EP disclosed