SCHEMBL9218688

SCHEMBL9218688

C=C(C)C(=O)CCOC(=O)n1ccnc1

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 4/20 0.35
TDP1 Q9NUW8 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.32
AHR P35869 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP19A1 P11511 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1148083 0.85 THRB (0.45) TBXAS1TDP1AHRCYP1A2CYP2D6
SCHEMBL13225859 0.81 THRB (0.49) TBXAS1TDP1AHRCYP1A2CYP2D6
SCHEMBL12016623 0.81 ALDH1A1 (0.39) TBXAS1TDP1EGLN3AHRCYP1A2
SCHEMBL2899421 0.78 AHR (0.40) TBXAS1TDP1AHRCYP1A2CYP2D6
SCHEMBL2033134 0.78 THRB (0.40) TBXAS1TDP1EGLN3AHRALDH1A1
SCHEMBL17589662 0.78 THRB (0.37) TBXAS1TDP1AHRALDH1A1CYP19A1
SCHEMBL12016622 0.77 TDP1 (0.40) TBXAS1TDP1EGLN3AHRCYP1A2
SCHEMBL12016620 0.77 TDP1 (0.44) TBXAS1TDP1EGLN3AHRCYP1A2
SCHEMBL10299924 0.76 CYP24A1 (0.36) TBXAS1TDP1EGLN3AHRCYP1A2
SCHEMBL10118389 0.76 TBXAS1 (0.37) TBXAS1TDP1EGLN3AHRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7112974-A None JP disclosed
JP-H07112974-A (METH)ACRYLATE DERIVATIVE NIPPON OIL & FATS CO LTD 1995-05-02 JP disclosed