SCHEMBL921987

SCHEMBL921987

Cc1ccc(Oc2ccc(CN)cc2)c(C)c1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.46
LIPG Q9Y5X9 1/20 0.44
NR3C1 P04150 1/20 0.41
CARM1 Q86X55 3/20 0.40
PRMT6 Q96LA8 3/20 0.40
SLC6A4 P31645 2/20 0.40
PRMT5 O14744 1/20 0.40
WDR77 Q9BQA1 1/20 0.40
ALDH1A1 P00352 1/20 0.39
MRGPRX4 Q96LA9 1/20 0.38
HTR2A P28223 1/20 0.38
KCNH2 Q12809 1/20 0.38
TAAR5 O14804 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
KEAP1 Q14145 1/20 0.38
NFE2L2 Q16236 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922082 0.86 ST14 (0.53) ST14SLC6A4ALDH1A1TAAR1KEAP1
SCHEMBL28452075 0.85 SLC6A4 (0.45) L3MBTL1LIPGSLC6A4ALDH1A1HTR2A
SCHEMBL12239030 0.85 ST14 (0.52) ST14L3MBTL1TAAR1
SCHEMBL12239009 0.83 ST14 (0.50) ST14L3MBTL1SLC6A4MRGPRX4HTR2A
SCHEMBL446449 0.83 AR (0.47) L3MBTL1LIPGSLC6A4ALDH1A1HTR2A
SCHEMBL30879515 0.83 L3MBTL1 (0.49) L3MBTL1LIPGNR3C1CARM1PRMT6
SCHEMBL920995 0.81 ST14 (0.47) ST14CARM1PRMT6SLC6A4HTR2A
SCHEMBL11528953 0.80 TEAD4 (0.61) ALDH1A1
SCHEMBL4368162 0.80 CARM1 (0.56) ST14NR3C1CARM1PRMT6SLC6A4
SCHEMBL12239016 0.80 ST14 (0.50) ST14L3MBTL1SLC6A4ALDH1A1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed
WO-2009107764-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS 住友化学株式会社 (JP) 2009-09-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885L3MBTL1 1292/4885LIPG 3664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.