Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 3/20 | 0.56 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.56 |
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16945359 | 0.83 | LOXL2 (0.49) | LOXL2ST14 | |
| SCHEMBL4369522 | 0.81 | CSNK2A1 (0.51) | MAOBLOXL2ST14HTR2ASLC6A4 | |
| SCHEMBL921987 | 0.80 | ST14 (0.53) | CARM1PRMT6ST14HTR2ASLC6A4 | |
| SCHEMBL12239030 | 0.79 | ST14 (0.52) | MAOBST14 | |
| SCHEMBL5553265 | 0.78 | CARM1 (0.47) | CARM1PRMT6MAOBHTR2ASLC6A4 | |
| SCHEMBL19175092 | 0.78 | SLC6A4 (0.50) | CARM1PRMT6HTR2ASLC6A4KCNH2 | |
| SCHEMBL4370586 | 0.77 | HSPB1 (0.54) | MAOBLOXL2ST14ROCK2ROCK1 | |
| SCHEMBL919783 | 0.77 | LOXL2 (0.73) | MAOBLOXL2ST14 | |
| SCHEMBL507354 | 0.76 | ST14 (0.52) | MAOBST14 | |
| SCHEMBL920995 | 0.75 | ST14 (0.47) | CARM1PRMT6ST14HTR2ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009117421-A2 | HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE | KALYPSYS, INC. (US) | 2009-09-24 | — | — | WO | disclosed |