SCHEMBL920995

SCHEMBL920995

CSc1ccc(Oc2ccc(CN)cc2)c(C)c1

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ST14 Q9Y5Y6 3/20 0.47
SLC6A4 P31645 13/20 0.46
SLC6A2 P23975 4/20 0.42
SLC6A3 Q01959 4/20 0.42
HRH3 Q9Y5N1 1/20 0.41
HTR2A P28223 1/20 0.38
KCNH2 Q12809 1/20 0.38
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11229125 0.83 ALDH1A1 (0.46) SLC6A4SLC6A2SLC6A3HRH3HTR2A
SCHEMBL921987 0.81 ST14 (0.53) ST14SLC6A4HTR2AKCNH2CARM1
SCHEMBL920206 0.80 ST14 (0.61) ST14SLC6A4SLC6A2SLC6A3HTR2A
SCHEMBL12239030 0.80 ST14 (0.52) ST14
SCHEMBL921804 0.76 SLC6A4 (0.42) SLC6A4SLC6A2SLC6A3HRH3HTR2A
SCHEMBL923687 0.76 AR (0.49) SLC6A4SLC6A2SLC6A3HRH3MAOA
SCHEMBL4368162 0.75 CARM1 (0.56) ST14SLC6A4HTR2AKCNH2CARM1
SCHEMBL16945359 0.74 LOXL2 (0.49) ST14
SCHEMBL922366 0.74 ST14 (0.44) ST14SLC6A4
SCHEMBL507354 0.74 ST14 (0.52) ST14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 ST14 708/4885SLC6A4 2590/4885SLC6A2 3667/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.