Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8312908 | 0.97 | KMT2A (0.45) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8313857 | 0.87 | KMT2A (0.35) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8314253 | 0.86 | KMT2A (0.36) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8318010 | 0.85 | KMT2A (0.47) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8317246 | 0.83 | KMT2A (0.45) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL9443610 | 0.83 | KMT2A (0.50) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL9538257 | 0.81 | KMT2A (0.49) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8314804 | 0.80 | SIGMAR1 (0.43) | KMT2ASMN1; SMN2ALDH1A1SIGMAR1TSHR | |
| SCHEMBL8876411 | 0.80 | KMT2A (0.51) | KMT2ASMN1; SMN2MEN1GAAKDM4E | |
| SCHEMBL8314523 | 0.80 | KMT2A (0.38) | KMT2ASMN1; SMN2MEN1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442073-B1 | Polycyclic 3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AG (DE) | 1995-01-25 | — | — | EP | disclosed |