Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | FAP | Q12884 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | CCR3 | P51677 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313857 | 0.87 | KMT2A (0.35) | SIGMAR1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8313154 | 0.85 | KMT2A (0.41) | SIGMAR1KMT2ADPP4TSHRPDE3B | |
| SCHEMBL8315795 | 0.84 | CCR1 (0.37) | KMT2ATSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8877223 | 0.84 | TSHR (0.46) | SIGMAR1KMT2ADPP4FAPDPP8 | |
| SCHEMBL8312908 | 0.83 | KMT2A (0.45) | SIGMAR1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8316915 | 0.83 | TSHR (0.46) | SIGMAR1KMT2ATSHRPDE3BPDE3A | |
| SCHEMBL9538321 | 0.81 | SIGMAR1 (0.49) | SIGMAR1KMT2ATSHRMAPK1RECQL | |
| SCHEMBL9220150 | 0.80 | KMT2A (0.44) | SIGMAR1KMT2ATSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL8314523 | 0.79 | KMT2A (0.38) | KMT2AMAPK1SMN1; SMN2ALDH1A1POLB | |
| SCHEMBL8314253 | 0.79 | KMT2A (0.36) | KMT2ARECQLLMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0501129-B1 | Substituted bicyclic 3-arylpyrrolidin-2,4-dion derivatives | BAYER AG (DE) | 1999-07-14 | — | — | EP | disclosed |