SCHEMBL922070

SCHEMBL922070

Cc1ccc(C(=O)NCc2cccc(Oc3cccc(Br)c3)c2)c(N)n1

nearest known ligand 0.51

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.51
LMNA P02545 2/20 0.51
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
USP2 O75604 1/20 0.48
MAPT P10636 2/20 0.47
CHRM4 P08173 2/20 0.46
PPARG P37231 8/20 0.46
PPARD Q03181 8/20 0.46
PPARA Q07869 8/20 0.46
THRB P10828 1/20 0.45
RXFP1 Q9HBX9 1/20 0.45
MMP13 P45452 1/20 0.44
ROCK2 O75116 1/20 0.44
ROCK1 Q13464 1/20 0.44
HSD17B10 Q99714 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL920516 0.93 MAPK14 (0.45) HPGDLMNAKDM4EALDH1A1USP2
SCHEMBL921419 0.93 MMP13 (0.48) HPGDLMNAKDM4EALDH1A1USP2
SCHEMBL920750 0.90 KDM4E (0.54) HPGDKDM4EALDH1A1USP2CHRM4
SCHEMBL922174 0.89 KDM4E (0.53) HPGDLMNAKDM4EALDH1A1USP2
SCHEMBL921580 0.88 MMP13 (0.58) HPGDKDM4EALDH1A1USP2CHRM4
SCHEMBL920306 0.88 HPGD (0.60) HPGDLMNAKDM4EALDH1A1USP2
SCHEMBL921751 0.88 HPGD (0.48) HPGDLMNAKDM4EALDH1A1USP2
SCHEMBL919651 0.88 MAPT (0.50) HPGDKDM4EALDH1A1USP2MAPT
SCHEMBL920568 0.88 MMP13 (0.57) HPGDLMNAKDM4EALDH1A1USP2
SCHEMBL920712 0.88 KMT2A (0.53) HPGDLMNAKDM4EALDH1A1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 HPGD 1273/4885LMNA 4812/4885KDM4E 3657/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.