SCHEMBL922085

SCHEMBL922085

Cc1ccc(C(=O)NCc2ccc(Oc3ccc(F)c(C(F)(F)F)c3)cc2)c(N)n1

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.42
PTPN7 P35236 1/20 0.41
DUSP3 P51452 1/20 0.41
CDK8 P49336 1/20 0.41
SCN9A Q15858 1/20 0.41
PPARG P37231 6/20 0.41
PPARD Q03181 6/20 0.41
PPARA Q07869 6/20 0.41
LIPG Q9Y5X9 1/20 0.41
PTGER4 P35408 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
P2RX7 Q99572 1/20 0.41
MAPK1 P28482 2/20 0.40
CHRM4 P08173 1/20 0.40
FLT1 P17948 1/20 0.40
LRRK2 Q5S007 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL921283 0.93 PPARG (0.42) MAPK14SCN9APPARGPPARDPPARA
SCHEMBL922230 0.91 MAPK14 (0.43) MAPK14PTPN7DUSP3CDK8LIPG
SCHEMBL919842 0.88 PTPN7 (0.40) MAPK14PTPN7DUSP3CDK8PPARG
SCHEMBL922052 0.88 PPARD (0.43) MAPK14SCN9APPARGPPARDPPARA
SCHEMBL921034 0.87 MAPK14 (0.57) MAPK14PPARGPPARDPPARAADORA2A
SCHEMBL922738 0.87 PPARD (0.46) PPARGPPARDPPARALIPGPTGER4
SCHEMBL920019 0.86 PPARA (0.49) MAPK14PPARGPPARDPPARA
SCHEMBL920318 0.85 MAPK14 (0.53) MAPK14PPARGPPARDPPARA
SCHEMBL920459 0.85 LIPG (0.55) MAPK14SCN9APPARGPPARDPPARA
SCHEMBL920363 0.85 EPHX2 (0.51) MAPK14PPARGPPARDPPARALIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885PTPN7 539/4885DUSP3 3122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.