SCHEMBL922052

SCHEMBL922052

Cc1ccc(C(=O)NCc2ccc(Oc3ccc(F)c(OC(F)(F)F)c3)cc2)c(N)n1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 9/20 0.43
PPARA Q07869 9/20 0.43
PPARG P37231 7/20 0.43
ADRB2 P07550 1/20 0.41
LIPG Q9Y5X9 1/20 0.41
PDE2A O00408 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA2B P29275 1/20 0.41
ADORA1 P30542 1/20 0.41
KLKB1 P03952 1/20 0.41
RIPK1 Q13546 1/20 0.40
EPHX2 P34913 1/20 0.40
NR1H4 Q96RI1 1/20 0.40
HTR2C P28335 1/20 0.40
MAPK14 Q16539 1/20 0.40
SCN9A Q15858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL922738 0.94 PPARD (0.46) PPARDPPARAPPARGADRB2LIPG
SCHEMBL921391 0.93 PPARA (0.43) PPARDPPARAPPARGADRB2LIPG
SCHEMBL921339 0.91 KLKB1 (0.42) PPARDPPARAPPARGLIPGPDE2A
SCHEMBL920363 0.88 EPHX2 (0.51) PPARDPPARAPPARGADRB2LIPG
SCHEMBL922085 0.88 MAPK14 (0.42) PPARDPPARAPPARGLIPGADORA2A
SCHEMBL921868 0.88 PPARD (0.40) PPARDPPARAPPARGLIPGPDE2A
SCHEMBL919993 0.87 PPARD (0.45) PPARDPPARAPPARGADRB2LIPG
SCHEMBL921462 0.87 PPARD (0.53) PPARDPPARAPPARGADRB2PDE2A
SCHEMBL921310 0.87 ALDH1A1 (0.45) PPARDPPARAPPARGADRB2PDE2A
SCHEMBL920558 0.86 LIPG (0.44) PPARDPPARAPPARGADRB2LIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 PPARD 360/4885PPARA 494/4885PPARG 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.