SCHEMBL922161

SCHEMBL922161

Cc1ccccc1Oc1ccc(CNC(=O)c2ccc(F)nc2N)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 2/20 0.56
HTT P42858 3/20 0.47
ALDH1A1 P00352 2/20 0.47
HPGD P15428 2/20 0.47
GAA P10253 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PTGER4 P35408 3/20 0.45
PTGER2 P43116 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
CARM1 Q86X55 2/20 0.44
PRMT6 Q96LA8 2/20 0.44
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
LIPG Q9Y5X9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL919884 0.90 CARM1 (0.54) HTTALDH1A1HPGDGAAATM
SCHEMBL921442 0.89 MAPK14 (0.58) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL921057 0.89 L3MBTL1 (0.48) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL920702 0.89 KDM4E (0.48) MAPK14HTTALDH1A1HPGDKDM4E
SCHEMBL921932 0.89 HTT (0.46) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL919908 0.88 RXFP1 (0.47) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL922229 0.88 HPGD (0.47) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL922774 0.88 L3MBTL1 (0.47) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL921103 0.88 MAPK14 (0.56) MAPK14HTTALDH1A1HPGDGAA
SCHEMBL921696 0.87 LMNA (0.54) MAPK14HTTALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MAPK14 905/4885HTT 2561/4885ALDH1A1 2743/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.